CONCOMITANT ‘C’ AND ‘G’ BANDS IN HUMAN CHROMOSOMES

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G and/or C-bands in plant chromosomes?

Similarities and differences become evident from comparisons of centromeric and non-centromeric banding patterns in plant and animal chromosomes. Similar to C and G-banding in animals (at least most of the reptiles, birds and mammals), centromeric and nucleolus-organizing region bands as well as interstitially and/or terminally located non-centromeric bands may occur in plants, depending on the...

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High-mobility group protein HMG-I localizes to G/Q- and C-bands of human and mouse chromosomes

Mammalian metaphase chromosomes can be identified by their characteristic banding pattern when stained with Giemsa dye after brief proteolytic digestion. The resulting G-bands are known to contain regions of DNA enriched in A/T residues and to be the principal location for the L1 (or Kpn 1) family of long interspersed repetitive sequences in human chromosomes. Here we report that antibodies rai...

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Toroidal bands in polytene chromosomes of Drosophila.

Results obtained from the thin-section electron microscopy of salivary gland chromosomes of Drosophila melanogaster mainly support the concept of cable-like organization of polytene chromosomes, with disk-like bands composed of parallel bundles of homologous chromomeres. Outward orientation of loop fibres may generally cause a toroidal bending in the chromomere bundles. Both longitudinal and tr...

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G+C content variation along and among Saccharomyces cerevisiae chromosomes.

Past analyses of the genome of the yeast Saccharomyces cerevisiae have revealed substantial regional variation in G+C content. Important questions remain, though, as to the origin, nature, significance, and generality of this variation. We conducted an extensive analysis of the yeast genome to try to answer these questions. Our results indicate that open reading frames (ORFs) with similar G+C c...

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Effects of Mitomycin C on Human Chromosomes

Mitomycin C (MC) is a chemically reactive antibiotic derived from Streptomyces caespitosus. The drug selectively inhibits DNA synthesis (2, 15, 29, 34, 39, 40, 43, 44, 49) and degrades cellular DNA but does not affect the synthesis of R N A or protein (31, 33, 40). MC induces bacteriophage production in lysogenic bacteria (23, 29), increases the rate of genetic recombination among mutant forms ...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1974

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197404000-00305